Table 1.
Clinical characteristics of human subjects
Control transplant patients (n=30) | AbMR Patients (n=9) | P | ||
---|---|---|---|---|
Age, mean (SD), y | 51.8 (14.4) | 38.9 (14.9) | 0.025 | |
Male, n (%) | 17 (56.7) | 3 (33.3) | 0.15 | |
Years since transplant, mean (SD) | 8.2 (7.0) | 2.15 (2.0) | 0.0002 | |
Any DSA MFI >500, n (%) | 9 (30) | 9 (100) | 0.0002 | |
C1q-binding DSA, n (%)*** | 5 (16.7) | 4 (66.7) | 0.018 | |
Serum Creatinine, mean (SD), mg/dL | 1.6 (0.4) | 3.24 (2.9) | 0.13 | |
Immunosuppression | ||||
CNI, n (%) | 30 (100) | 9 (100) | 1.0 | |
mTORi, n (%) | 8 (26.7) | 1 (16.7) | 0.25 | |
Mycophenolate, n (%) | 16 (53.3) | 8 (83.3) | 0.25 | |
Prednisone, n (%) | 27 (90) | 8 (83.3) | 0.44 | |
Samples missing for 3 AbMR subjects for C1q-binding assay