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. 2020 Mar 18;48(8):4256–4273. doi: 10.1093/nar/gkaa174

Figure 6.

Figure 6.

Somatic genes are aberrantly expressed in heat-stressed mut-16 and hrde-1 mutants. (A) Percentages of gonad-specific and soma-specific genes represented in the genes specifically up-regulated in mut-16 and hrde-1 mutants at 25°C. Enrichment analysis for spermatogenesis, oogenesis, gender-neutral genes, and muscle-specific and neuronal-specific genes among the genes up-regulated in both mut-16 and hrde-1 mutants at elevated temperature is shown in the table below. n.s. denotes not significant and indicates a P-value > 0.05 and *** indicates a P-value ≤ 0.001. (B) Enrichment analysis for small RNA pathway target genes represented in the genes up-regulated in both mut-16 and hrde-1 mutants at elevated temperature. n.a. denotes ‘not applicable’ when zero genes were represented. n.s. denotes not significant and indicates a P-value > 0.05. (C) Gene enrichment analysis was performed using WormExp (log10Q ≥ 2 and FDR < 0.05) for genes up-regulated in mut-16 and hrde-1 mutants at 25°C. See Supplementary Figure S4 for complete list of enriched gene sets.