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. 2020 Mar 23;48(8):3999–4012. doi: 10.1093/nar/gkaa172

Figure 6.

Figure 6.

Editing is globally higher in GA versus GFL. (A) Mean editing levels over 36 002 editing sites in GA and GFL. Error bars represent SD over four replicates. (B) Editing index calculated using 36 002 editing sites in GA and GFL. Error bars represent SD over four replicates. (C) Number of sites with significantly higher editing in GA and in GFL and with no significant change in editing. (D) Histogram of the difference between editing in GA and editing in GFL in each site. Higher editing level in the GA is observed for 92% of the sites. (E) Sanger sequencing validation of differential editing sites. Error bars for the Illumina represent SEM over four replicates. Error bars for GA Sanger bars represent SEM over two replicates. No bars in the Sanger GFL lanes indicate that editing was not detected.