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. 2020 Mar 11;82(4):467–474. doi: 10.1292/jvms.19-0450

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©2020 The Japanese Society of Veterinary Science

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)

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Fig. 3. — Representative images of histopathological findings in the pancreas in the control group (A), diabetic untreated group (B), dapagliflozin (0.1 mg/kg)-treated group (C), high-dose insulin (3–5 U/rat) group (D), combined treatment of insulin (1.5–2.5 U/rat) and dapagliflozin (0.1 mg/kg) (E). (A) A normal islet of Langerhans. (B, C) An atrophic islet of Langerhans. (D, E) A normal-sized islet of Langerhans. Note the swollen cells in the center and small, densely packed cells in the periphery. H&E stain. Scale bar=100 µm.