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. 2020 Apr 7;23(2):115–128. doi: 10.4048/jbc.2020.23.e24

Table 4. Trends in age-standardized incidence rates for breast cancer according to Joinpoint analysis (1999–2017).

	AAPC (1999–2017)	Trend 1			Trend 2
	AAPC (1999–2017)	Period	APC	95% CI	Period	APC	95% CI
All breast cancer	+5.7^*	1999–2007	+7.4^*	6.2–8.6	2007–2017	+4.9^*	4.3–5.5
Invasive breast cancer	+5.0^*	1999–2002	+10.0^*	3.8–16.5	2002–2017	+4.7^*	4.4–5.1
Carcinoma in situ	+11.1^*	1999–2008	+18.0^*	15.7–20.3	2008–2017	+7.9^*	6.8–8.9

AAPC = average annual percentage change (%); APC = annual percent change (%); CI = confidence interval.

^*The APC or AAPC is a significantly different from zero (p < 0.05).