Table II.
HLA A and B antibodies detected in patients | HLA alleles of the incompatible platelet product given immediately after eculizumab | |
---|---|---|
Patient 1- treatment 1 | A: 02, 34 | HLA A: 23, 24 |
B: 42, 67, 55, 8, 54, 81, 41*, 07*, 82* | HLA B: 38, 41 | |
Patient 5 | A: 02, 69, 68, 24, 23, 01, 11 | HLA A: 01, 2901 |
B: 51, 35, 53, 71, 49, 75, 8, 78, 50, 77, 56, 52, 57, 72, 62, 63, 58, 46, 59 | HLA B: 8, 1302 | |
Patient 7 | A: 02, 68, 69, 80, 24, 11, 01, 66, 34, 25, 26, 3, 32, 36, 43, 33, 29, 74, 31 | HLA A: 23, 32 |
B: 07, 49, 42, 67, 81, 55, 56, 82, 57, 60, 50, 13, 61, 27, 58, 44, 45, 41, 48, 52, 73, 47, 51, 54, 62, 76, 63, 8, 72, 59, 71, 77, 53 | HLA B: 35, 39 | |
Patient 8 | A: 23, 32, 24, 25, 01, 31*, 30*, 33*, 74* | HLA A: 02, 03 HLA B: 07, 35 |
B: 57, 44, 49, 63, 76, 58, 45, 51, 77, 52, 13, 59, 53, 27, 38, 62, 47, 41, 37, 50, 61, 72, 60, 75, 82, 56, 55, 42, 67, 8, 07*, 81*, 65*, 64*, 48*, 39*, 73*, 18*, 46* | HLA A: 03, 68 HLA B: 14†, 35 |
Numbers shown in bold represent HLA A and B antibodies detected in the patient and HLA A and B alleles expressed in the transfused HLA-incompatible platelet product.
HLA antibodies detected historically in the serum of thrombocytopenic patients.
B64 and 65 are sero-equivalents of B14.