Table 5.
Adjusted and Weighted Risk Ratios for Acetaminophen Use During Pregnancy and Clinical Behavioral Outcomes, Childhood Assessment
| Percent in Clinical Rangea |
Risk Ratios and 95% Confidence Intervals | |||
|---|---|---|---|---|
| n (%) | Adjustedb | SIPWc | Indication Adjustedd | |
| Teacher Report Form | ||||
| Internalizing | 57 (10.2) | 0.80 (0.44, 1.45) | 1.08 (0.62, 1.88) | 0.86 (0.48, 1.56) |
| Externalizing | 54 (9.6) | 1.00 (0.56, 1.78) | 0.99 (0.59, 1.67) | 0.90 (0.50, 1.62) |
| Total Problems | 72 (12.9) | 0.82 (0.48, 1.43) | 1.03 (0.65, 1.64) | 0.84 (0.48, 1.47) |
| Missing TRF | 66 | |||
| Child Behavior Checklist | ||||
| Internalizing | 71 (12.7) | 1.52 (0.85, 2.70) | 1.46 (0.93, 2.31) | 1.04 (0.61, 1.81) |
| Externalizing | 68 (12.1) | 1.60 (0.91, 2.81) | 1.61 (0.96, 2.69) | 1.26 (0.71, 2.22) |
| Total Problems | 63 (11.3) | 1.93 (0.99, 3.76) | 1.77 (1.03, 3.06) | 1.31 (0.67, 2.58) |
| Missing CBCL | 4 | |||
a
number and percentage of subjects meeting clinical definition for behavioral problems using a t-score cutoff of 60
b
adjusted for maternal age, race, education, marital status, smoking, drinking, and parity
c
weighted by SIPW (stabilized inverse probability weights), c-statistic 0.73, weights range from 0.47–3.8
d
additionally adjusted for indication (headache, upper respiratory infection, fever, pain)