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. 2020 Apr 1;27(4):363–374. doi: 10.5551/jat.50385

Table 3. Multivariable adjusted hazard ratios and 95% confidence intervals of non-HDL cholesterol (non-HDL-C) quintiles in relation to stroke subtypes in men.

Non-HDL-C quintile
Subtypes of stroke Q1 Q2 Q3 Q4 Q5 P for linear trend
Subarachnoid hemorrhage Cases, n 13 9 6 4 8
Model 1 1 0.68 (0.29–1.58) 0.44 (0.17–1.16) 0.30 (0.10–0.92) 0.61 (0.25–1.49) 0.06
Model 2 1 0.79 (0.33–1.89) 0.55 (0.20–1.49) 0.40 (0.12–1.31) 0.86 (0.32–2.30) > 0.2
 
Intracerebral hemorrhage Cases, n 59 49 46 45 32
Model 1 1 0.81 (0.56–1.19) 0.75 (0.51–1.10) 0.78 (0.53–1.15) 0.57 (0.37–0.87) 0.008
Model 2 1 0.82 (0.56–1.20) 0.74 (0.50–1.10) 0.79 (0.53–1.19) 0.55 (0.35–0.87) 0.010
 
Ischemic stroke Cases, n 107 109 112 89 126
Model 1 1 1.03 (0.79–1.35) 1.05 (0.81–1.37) 0.88 (0.66–1.16) 1.28 (0.99–1.66) 0.10
Model 2 1 0.99 (0.76–1.30) 0.99 (0.75–1.30) 0.81 (0.60–1.09) 1.13 (0.86–1.49) > 0.2
 
Lacunar infarction Cases, n 40 49 43 38 53
Model 1 1 1.23 (0.81–1.87) 1.08 (0.70–1.66) 1.00 (0.64–1.55) 1.41 (0.93–2.13) 0.13
Model 2 1 1.19 (0.78–1.81) 1.01 (0.65–1.57) 0.92 (0.58–1.46) 1.25 (0.80–1.94) > 0.2
 
Large-artery occlusive infarction Cases, n 15 25 20 25 32
Model 1 1 1.68 (0.89–3.19) 1.33 (0.68–2.59) 1.75 (0.92–3.33) 2.34 (1.26–4.33) 0.005
Model 2 1 1.63 (0.86–3.11) 1.18 (0.59–2.34) 1.60 (0.82–3.09) 2.05 (1.07–3.93) 0.033
 
Embolic infarction Cases, n 43 30 41 24 37
Model 1 1 0.71 (0.45–1.13) 0.95 (0.62–1.46) 0.59 (0.36–0.97) 0.94 (0.60–1.46) > 0.2
Model 2 1 0.68 (0.42–1.09) 0.94 (0.61–1.47) 0.55 (0.33–0.93) 0.84 (0.52–1.35) > 0.2

Model 1 was adjusted for age and community. Model 2 was further adjusted for smoking status (never, ex-, < 20, or ≥ 20 cigarettes/day), alcohol intake (0, 1–150, 151–300, or ≥ 301 g/week), sports at leisure time (rarely, 1–2, 3–4 times/week, or almost every day), body mass index, systolic blood pressure, use of antihypertensive agents, diabetes, HDL-C, and use of antilipemic agents. Linear trends were tested by using continuous values of non-HDL-C.