Table 3. Multivariable adjusted hazard ratios and 95% confidence intervals of non-HDL cholesterol (non-HDL-C) quintiles in relation to stroke subtypes in men.
Non-HDL-C quintile |
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---|---|---|---|---|---|---|---|
Subtypes of stroke | Q1 | Q2 | Q3 | Q4 | Q5 | P for linear trend | |
Subarachnoid hemorrhage | Cases, n | 13 | 9 | 6 | 4 | 8 | |
Model 1 | 1 | 0.68 (0.29–1.58) | 0.44 (0.17–1.16) | 0.30 (0.10–0.92) | 0.61 (0.25–1.49) | 0.06 | |
Model 2 | 1 | 0.79 (0.33–1.89) | 0.55 (0.20–1.49) | 0.40 (0.12–1.31) | 0.86 (0.32–2.30) | > 0.2 | |
Intracerebral hemorrhage | Cases, n | 59 | 49 | 46 | 45 | 32 | |
Model 1 | 1 | 0.81 (0.56–1.19) | 0.75 (0.51–1.10) | 0.78 (0.53–1.15) | 0.57 (0.37–0.87) | 0.008 | |
Model 2 | 1 | 0.82 (0.56–1.20) | 0.74 (0.50–1.10) | 0.79 (0.53–1.19) | 0.55 (0.35–0.87) | 0.010 | |
Ischemic stroke | Cases, n | 107 | 109 | 112 | 89 | 126 | |
Model 1 | 1 | 1.03 (0.79–1.35) | 1.05 (0.81–1.37) | 0.88 (0.66–1.16) | 1.28 (0.99–1.66) | 0.10 | |
Model 2 | 1 | 0.99 (0.76–1.30) | 0.99 (0.75–1.30) | 0.81 (0.60–1.09) | 1.13 (0.86–1.49) | > 0.2 | |
Lacunar infarction | Cases, n | 40 | 49 | 43 | 38 | 53 | |
Model 1 | 1 | 1.23 (0.81–1.87) | 1.08 (0.70–1.66) | 1.00 (0.64–1.55) | 1.41 (0.93–2.13) | 0.13 | |
Model 2 | 1 | 1.19 (0.78–1.81) | 1.01 (0.65–1.57) | 0.92 (0.58–1.46) | 1.25 (0.80–1.94) | > 0.2 | |
Large-artery occlusive infarction | Cases, n | 15 | 25 | 20 | 25 | 32 | |
Model 1 | 1 | 1.68 (0.89–3.19) | 1.33 (0.68–2.59) | 1.75 (0.92–3.33) | 2.34 (1.26–4.33) | 0.005 | |
Model 2 | 1 | 1.63 (0.86–3.11) | 1.18 (0.59–2.34) | 1.60 (0.82–3.09) | 2.05 (1.07–3.93) | 0.033 | |
Embolic infarction | Cases, n | 43 | 30 | 41 | 24 | 37 | |
Model 1 | 1 | 0.71 (0.45–1.13) | 0.95 (0.62–1.46) | 0.59 (0.36–0.97) | 0.94 (0.60–1.46) | > 0.2 | |
Model 2 | 1 | 0.68 (0.42–1.09) | 0.94 (0.61–1.47) | 0.55 (0.33–0.93) | 0.84 (0.52–1.35) | > 0.2 |
Model 1 was adjusted for age and community. Model 2 was further adjusted for smoking status (never, ex-, < 20, or ≥ 20 cigarettes/day), alcohol intake (0, 1–150, 151–300, or ≥ 301 g/week), sports at leisure time (rarely, 1–2, 3–4 times/week, or almost every day), body mass index, systolic blood pressure, use of antihypertensive agents, diabetes, HDL-C, and use of antilipemic agents. Linear trends were tested by using continuous values of non-HDL-C.