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. 2020 Apr 1;27(4):363–374. doi: 10.5551/jat.50385

Table 5. Multivariable adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of one standard deviation (SD) increase in non-HDL cholesterol related to the incidence of coronary heart disease (CHD) and stroke subtypes according to the presence/absence of overweight, hypertension, and hypertriglyceridemia in men.

Cardiovascular disease outcomes
CHD
Intracerebral hemorrhage
Large-artery occlusive infarction
Cases, n HR (95% CI)* P for interaction Cases, n HR (95% CI)* P for interaction Cases, n HR (95% CI)* P for interaction
Overweight
    No 111 1.71 (1.49–1.97) 0.91 164 0.79 (0.66–0.94) 0.22 71 1.22 (0.96–1.56) 0.72
    Yes 66 1.55 (1.21–1.98) 67 0.96 (0.74–1.24) 46 1.28 (0.94–1.74)
 
Hypertension
    No 57 1.87 (1.56–2.23) 0.32 81 0.90 (0.70–1.15) 0.45 47 1.34 (1.03–1.75) 0.34
    Yes 120 1.55 (1.30–1.85) 150 0.81 (0.68–0.96) 70 1.15 (0.90–1.47)
 
Hypertriglyceridemia
    No 143 1.62 (1.37–1.91) 0.97 202 0.85 (0.73–1.00) 0.49 103 1.16 (0.94–1.43) 0.19
    Yes 34 1.60 (1.22–2.09) 29 0.64 (0.42–0.98) 14 1.83 (1.20–2.79)
 
Alcohol drinking
    No 91 1.95 (1.60–2.36) 0.008 77 0.86 (0.68–1.10) 0.34 48 1.19 (0.89–1.58) 0.93
    Yes 86 1.49 (1.24–1.78) 154 0.83 (0.69–1.00) 69 1.28 (1.00–1.62)
*

Adjusted for age, smoking status (never, ex-, < 20, or ≥ 20 cigarettes/day), alcohol intake (0, 1–150, 151–300, or ≥ 301 g/week), sports at leisure time (rarely, 1–2, 3–4 times/week, or almost every day), and body mass index stratified by community. When stratified by alcohol drinking status, it was excluded from the model. HRs are expressed according to SD increase in non-HDL-C.