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. 2020 Apr 1;27(4):363–374. doi: 10.5551/jat.50385

Supplemental Table 1. Multivariable adjusted hazard ratio of non-HDLC related to CHD and stroke subtypes in men.

Quintile of non-HDL cholesterol concentrations
P for trend
Q1 Q2 Q3 Q4 Q5
Excluding the first 3-yr follow-up period
(n = 515 for CHD and n = 613 for stroke)
 
    Men CHD 1 1.58 (0.72–3.46) 2.81 (1.37–5.77) 3.11 (1.52–6.36) 4.38 (2.18–8.80) <0.001
Intracerebral hemorrhage 1 0.82 (0.55–1.24) 0.71 (0.46–1.09) 0.83 (0.54–1.27) 0.55 (0.34–0.89) 0.016
Large–artery occlusive infarction 1 1.63 (0.85–3.10) 1.11 (0.55–2.23) 1.48 (0.75–2.89) 2.00 (1.04–3.84) 0.045
 
    Women CHD 1 1.26 (0.55–2.89) 1.62 (0.74–3.53) 1.79 (0.83–3.87) 2.04 (0.95–4.38) 0.013
Intracerebral hemorrhage 1 0.76 (0.49–1.18) 0.81 (0.52–1.24) 0.64 (0.41–1.02) 0.98 (0.64–1.52) 0.72
Large-artery occlusive infarction 1 0.87 (0.42–1.78) 0.77 (0.38–1.59) 1.23 (0.63–2.38) 0.78 (0.38–1.61) 0.83
 
Excluding those who used antilipemic agents
(n = 939)
 
    Men CHD 1 2.05 (0.97–4.34) 2.81 (1.37–5.75) 3.66 (1.81–7.40) 5.14 (2.58–10.2) < 0.001
Intracerebral hemorrhage 1 0.82 (0.56–1.20) 0.74 (0.50–1.11) 0.78 (0.52–1.18) 0.52 (0.33–0.83) 0.005
Large-artery occlusive infarction 1 1.62 (0.85–3.10) 1.17 (0.59–2.32) 1.47 (0.75–2.88) 2.02 (1.06–3.88) 0.05
 
    Women CHD 1 1.25 (0.57–2.78) 1.53 (0.72–3.25) 1.61 (0.76–3.41) 2.07 (0.99–4.32) 0.018
Intracerebral hemorrhage 1 0.75 (0.50–1.13) 0.70 (0.46–1.06) 0.64 (0.42–0.99) 0.89 (0.59–1.34) 0.92
Large–artery occlusive infarction 1 0.82 (0.41–1.68) 0.80 (0.40–1.61) 1.19 (0.62–2.28) 0.77 (0.37–1.58) 0.83
 
Excluding those with HDL-C ≥ 90 mg/dl
(n = 847)
 
    Men CHD 1 1.72 (0.83–3.57) 2.51 (1.26–5.01) 3.10 (1.58–6.09) 4.42 (2.29–8.55) < 0.001
Intracerebral hemorrhage 1 0.88 (0.59–1.31) 0.78 (0.52–1.17) 0.85 (0.56–1.29) 0.59 (0.37–0.94) 0.022
Large-artery occlusive infarction 1 1.93 (0.96–3.87) 1.41 (0.68–2.93) 1.90 (0.94–3.85) 2.44 (1.22–4.89) 0.008
 
    Women CHD 1 1.42 (0.63–3.20) 1.74 (0.80–3.76) 1.77 (0.82–3.81) 2.12 (0.99–4.53) 0.015
Intracerebral hemorrhage 1 0.67 (0.45–1.02) 0.63 (0.42–0.96) 0.60 (0.39–0.91) 0.82 (0.55–1.23) 0.66
Large-artery occlusive infarction 1 0.90 (0.44–1.84) 0.76 (0.37–1.55) 1.25 (0.65–2.41) 0.76 (0.37–1.57) 0.91

Sex-specified hazard ratios were adjusted for age, smoking status (never, ex-, < 20, or ≥ 20 cigarettes/day in men; or current smoker or not in women), alcohol intake (0, 1–150, 151–300, or ≥ 301 g/week in men; or ≥ 1 day/week alcohol drinker or not in women), sports during leisure time (rarely, 1–2, 3–4 times/week, or almost every day), body mass index, menopause (women only), systolic blood pressure, use of antihypertensive agents, diabetes, HDL-C, and use of antilipemic agents stratified by community.