Supplemental Table 1. Multivariable adjusted hazard ratio of non-HDLC related to CHD and stroke subtypes in men.
Quintile of non-HDL cholesterol concentrations |
P for trend | ||||||
---|---|---|---|---|---|---|---|
Q1 | Q2 | Q3 | Q4 | Q5 | |||
Excluding the first 3-yr follow-up period (n = 515 for CHD and n = 613 for stroke) |
|||||||
Men | CHD | 1 | 1.58 (0.72–3.46) | 2.81 (1.37–5.77) | 3.11 (1.52–6.36) | 4.38 (2.18–8.80) | <0.001 |
Intracerebral hemorrhage | 1 | 0.82 (0.55–1.24) | 0.71 (0.46–1.09) | 0.83 (0.54–1.27) | 0.55 (0.34–0.89) | 0.016 | |
Large–artery occlusive infarction | 1 | 1.63 (0.85–3.10) | 1.11 (0.55–2.23) | 1.48 (0.75–2.89) | 2.00 (1.04–3.84) | 0.045 | |
Women | CHD | 1 | 1.26 (0.55–2.89) | 1.62 (0.74–3.53) | 1.79 (0.83–3.87) | 2.04 (0.95–4.38) | 0.013 |
Intracerebral hemorrhage | 1 | 0.76 (0.49–1.18) | 0.81 (0.52–1.24) | 0.64 (0.41–1.02) | 0.98 (0.64–1.52) | 0.72 | |
Large-artery occlusive infarction | 1 | 0.87 (0.42–1.78) | 0.77 (0.38–1.59) | 1.23 (0.63–2.38) | 0.78 (0.38–1.61) | 0.83 | |
Excluding those who used antilipemic agents (n = 939) |
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Men | CHD | 1 | 2.05 (0.97–4.34) | 2.81 (1.37–5.75) | 3.66 (1.81–7.40) | 5.14 (2.58–10.2) | < 0.001 |
Intracerebral hemorrhage | 1 | 0.82 (0.56–1.20) | 0.74 (0.50–1.11) | 0.78 (0.52–1.18) | 0.52 (0.33–0.83) | 0.005 | |
Large-artery occlusive infarction | 1 | 1.62 (0.85–3.10) | 1.17 (0.59–2.32) | 1.47 (0.75–2.88) | 2.02 (1.06–3.88) | 0.05 | |
Women | CHD | 1 | 1.25 (0.57–2.78) | 1.53 (0.72–3.25) | 1.61 (0.76–3.41) | 2.07 (0.99–4.32) | 0.018 |
Intracerebral hemorrhage | 1 | 0.75 (0.50–1.13) | 0.70 (0.46–1.06) | 0.64 (0.42–0.99) | 0.89 (0.59–1.34) | 0.92 | |
Large–artery occlusive infarction | 1 | 0.82 (0.41–1.68) | 0.80 (0.40–1.61) | 1.19 (0.62–2.28) | 0.77 (0.37–1.58) | 0.83 | |
Excluding those with HDL-C ≥ 90 mg/dl (n = 847) |
|||||||
Men | CHD | 1 | 1.72 (0.83–3.57) | 2.51 (1.26–5.01) | 3.10 (1.58–6.09) | 4.42 (2.29–8.55) | < 0.001 |
Intracerebral hemorrhage | 1 | 0.88 (0.59–1.31) | 0.78 (0.52–1.17) | 0.85 (0.56–1.29) | 0.59 (0.37–0.94) | 0.022 | |
Large-artery occlusive infarction | 1 | 1.93 (0.96–3.87) | 1.41 (0.68–2.93) | 1.90 (0.94–3.85) | 2.44 (1.22–4.89) | 0.008 | |
Women | CHD | 1 | 1.42 (0.63–3.20) | 1.74 (0.80–3.76) | 1.77 (0.82–3.81) | 2.12 (0.99–4.53) | 0.015 |
Intracerebral hemorrhage | 1 | 0.67 (0.45–1.02) | 0.63 (0.42–0.96) | 0.60 (0.39–0.91) | 0.82 (0.55–1.23) | 0.66 | |
Large-artery occlusive infarction | 1 | 0.90 (0.44–1.84) | 0.76 (0.37–1.55) | 1.25 (0.65–2.41) | 0.76 (0.37–1.57) | 0.91 |
Sex-specified hazard ratios were adjusted for age, smoking status (never, ex-, < 20, or ≥ 20 cigarettes/day in men; or current smoker or not in women), alcohol intake (0, 1–150, 151–300, or ≥ 301 g/week in men; or ≥ 1 day/week alcohol drinker or not in women), sports during leisure time (rarely, 1–2, 3–4 times/week, or almost every day), body mass index, menopause (women only), systolic blood pressure, use of antihypertensive agents, diabetes, HDL-C, and use of antilipemic agents stratified by community.