Table 2. Breakdown of values about aHUS and secondary TMA.
| Value ranges and points | aHUS n (%) | secondary TMA n (%) | ||
|---|---|---|---|---|
| PT-ratio | < 1.25 | 0p | 11 (73) | 16 (80) |
| 1.25 ≤ – < 1.67 | 1p | 4 (27) | 2 (10) | |
| ≥ 1.67 | 2p | 0 (0) | 2 (10) | |
| APTT (sec) | ≤ 33 | 8 (53) | 8 (40) | |
| > 33 | 7 (47) | 12 (60) | ||
| FDP (µg/mL) | < 10 | 0p | 7 (47) | 9 (45) |
| 10 ≤ – < 20 | 1p | 4 (27) | 6 (30) | |
| 20 ≤ – < 40 | 2p | 3 (20) | 3 (15) | |
| ≥ 40 | 3p | 1 (6) | 2 (10) | |
| Fibrinogen (mg/dl) | > 150 | 0p | 11 (73) | 17 (85) |
| 100 ≤ – < 150 | 1p | 4 (27) | 2 (10) | |
| ≤ 100 | 2p | 0 (0) | 1 (5) | |
| AT (%) | > 70 | 0p | 15 (100) | 17 (85) |
| ≤ 70 | 1p | 0 (0) | 3 (15) | |
| FMC (ug/ml) | ≤ 12 | 0p | 13 (87) | 12 (60) |
| > 12 | 1p | 2 (13) | 8 (40) | |
| PIC (ug/ml) | < 0.8 | 0 (0) | 2 (10) | |
| ≥ 0.8 | 15 (100) | 18 (90) | ||
| VWF:Ag (%) | < 138 | 4 (27) | 10 (50) | |
| ≥ 138 | 11 (73) | 10 (50) | ||
P; points, aHUS; atypical hemolytic uremic syndrome, secondary TMA; secondary thrombotic microangiopathy, n; number, AT; antithombin, FMC; fibrin monomer complex, PIC; Plasmin-α2 plasmin inhibitor complex, VWF:Ag; von Willebrand factor antigen