Table 1.
Demographic characteristics of patients; HCV, co-infected HCV/HIV and HCV/CKD (n = 313)
| Demographic characteristics | Total (n = 313) n (%) |
HCV (n = 154) n (%) |
HCV/HIV (n = 124) n (%) |
HCV/CKD (n = 35) n (%) |
|---|---|---|---|---|
| Gender | ||||
| Female | 79 (25.2) | 50 (32.5) | 16 (12.9) | 13 (37.1) |
| Male | 234 (74.8) | 104 (67.5) | 108 (87.1) | 22 (62.9) |
| Age (years) | ||||
| Mean (SD) | 51.9 (11.1) | 50.3 (12.4) | 46.10 (10.4) | 59.23 (10.6) |
| Ethnicity/race | ||||
| Asian or Asian British | 47 (15.0) | 32 (20.8) | 3 (2.4) | 12 (34.3) |
| White | 180 (57.5) | 56 (36.4) | 104 (83.9) | 20 (55.6) |
| Black, African, Caribbean or black British | 21 (6.7) | 7 (4.5) | 11 (8.9) | 3 (8.6) |
| Mixed or multiple ethnic group | 2 (0.6) | 1 (0.6) | 1 (0.8) | – |
| Other ethnic group | 5 (1.6) | 5 (3.2) | – | |
| Prefer not to say | 58 (18.5) | 53 (34.4) | 5 (4.0) | – |
| Mode of infection | ||||
| Heterosexual/MSM | 10 (3.2) | – | 8 (6.5) | 2 (5.7) |
| IDU/PWID | 102 (32.6) | 13 (8.4) | 80 (64.5) | 9 (25.7) |
| Iatrogenic/non-occupational | 31 (9.9) | 8 (5.2) | 4 (3.2) | 19 (54.3) |
| Not known | 170 (54.3) | 133 (86.4) | 32 (25.8) | 5 (14.3) |
| Genotype | ||||
| 1/1a | 113 (36.1) | 39 (25.3) | 63 (50.8) | 11 (31.4) |
| 1b | 50 (16.0) | 29 (18.8) | 13 (10.5) | 8 (22.9) |
| 2 | 5 (1.6) | 3 (1.9) | 2 (1.6) | – |
| 3/3a | 110 (35.1) | 70 (45.5) | 26 (21.0) | 14 (40.0) |
| 4/4d | 33 (10.5) | 12 (7.8) | 19 (15.3) | 2 (5.7) |
| 5a | 2 (0.6) | 1 (0.6) | 1 (0.8) | – |
| Baseline viral loada | ||||
| Very low viremic | 14 (4.5) | 6 (3.9) | 8 (6.5) | – |
| Low viremic | 37 (11.8) | 11 (7.1) | 22 (17.7) | 4 (11.4) |
| Moderate viremic | 140 (44.7) | 83 (53.9) | 42 (33.9) | 15 (42.9) |
| High viremic | 122 (39.0) | 54 (35.1) | 52 (41.9) | 16 (45.7) |
| Liver disease status | ||||
| Non cirrhotic | 192 (61.3) | 68 (44.2) | 102 (82.3) | 22 (62.9) |
| Cirrhotic | 121 (38.7) | 86 (55.8) | 22 (17.7) | 13 (37.1) |
HIV human immunodeficiency virus, CKD chronic kidney disease, SD standard deviation, IDU injecting drug user, PWID patient who inject drugs, MSM men who have sex with men
aViral load is represented as; very low viremic = less than 8000 IU/ml, low viremic = 8001–20,000 IU/ml, moderate viremic = 20,001–800,000 IU/ml, and high viremic = greater than 800,000 IU/ml