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. 2020 Apr 30;11:2107. doi: 10.1038/s41467-020-15779-8

Fig. 7. Extended haplotype homozygosity and bifurcation plots for pfcrt K76T.

Fig. 7

a, b Display extended haplotype homozygosity (EHH) curves from the monoclonal samples with no missing genotype data 200 kb upstream and downstream from the K76T core single-nucleotide polymorphism in centimorgans among the samples from the eastern Democratic Republic of the Congo (DRC) and western DRC. c, d Show haplotype bifurcation plots with respect to the core allele ancestry and the eastern DRC and western DRC for a subsetted region. Position is considered in kilobases, and segregating sites for each haplotype are displayed at the nodes. Overall, there is strong evidence for recent positive selection of the pfcrt CVIET haplotype in the west that is mitigated in the east.