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. 2020 May 1;5:60. doi: 10.1038/s41392-020-0150-x

Fig. 4.

Fig. 4

The pathways of DNA double-strand break repair. The nonhomologous end-joining (NHEJ) pathway is an error-prone repair pathway that functions through the cell cycle. The homologous recombination pathway is an error-free repair pathway that requires intact homologous DNA as a repair template and is active in the later S and G2 phases. The alternative end-joining (a-EJ) pathway, which repairs DNA double-strand breaks (DSBs), is initiated by end resection that generates 3′ single strand