Table 4.

Coefficients and ANOVA results for reduced combinatorial model

Terms	Coefficient	P value	Coefficient
	(Scaled and centered)		(Raw data)
Constant	7.96	< 0.0001	6.63
TOI	0.07	0.0319	0.05
ID	− 0.11	0.0108	20.24
ICD	− 0.06	0.2396	4.10
ID * ID	− 0.61	0.0192	− 250.71
ICD * ICD	− 0.14	0.1359	− 3.51
TOI * ID	− 0.10	0.0054	1.00
TOI * ICD	− 0.09	0.0099	− 0.23
ID * ICD	− 0.14	0.0143	− 14.04
Lack of fit	–	0.28
R2	–	0.83
Adjusted R2	–	0.72
Q2	–	0.47