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Six types of NHases with different gene organizations. (A) The gene order of < α-subunit> < β-subunit><activator>; (B) the gene order of < β-subunit> < α-subunit><activator>; (C) the gene order of < α-subunit> < β-subunit> < γ-subunit><activator>; (D) the gene order of < α-subunit><activator> < β-subunit>; (E) the gene order of < β-subunit> < α-subunit>; (F) the gene order of solo-subunit NHase.
