TABLE 2.

Selected mutations found in evolved clones.*^‡

* “Annotation” column code: “ISH *** mediated” = flanking ISH elements, if relevant. Mutation codes: blue = missense, green = silent. “Gene” column code: (mutation starts or ends before this gene name), → ← indicates gene directionality, [mutation starts, ends, or is entirely contained within this gene name], “-” indicates intervening omitted genes found in description, “/” indicates mutation is between two genes. Highlight indicates mutations associated with acid evolution. ^‡This chart does not indicate shared lineage through identical mutations. For a complete list of mutations, see Supplementary Tables S1–S3.