TABLE 2.
Univariate Cox regression analysis and multivariate Cox regression analysis outcomes based on methylation risk score and other clinical factors.
Univariate Cox regression analysis |
Multivariate Cox regression analysis |
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Characteristics | HR | HR.95L | HR.95H | p value | HR | HR.95L | HR.95H | p value |
Score | 2.738045421 | 2.048628528 | 3.659469066 | 1.01E-11 | 2.510661624 | 1.788829617 | 3.523768687 | 1.02E-07 |
Estrogen receptor status | 0.692324993 | 0.342239438 | 1.400522099 | 0.306355543 | 0.768993041 | 0.260500851 | 2.270051305 | 0.634356191 |
Progesterone receptor status | 0.592458976 | 0.30230991 | 1.161085454 | 0.127286775 | 0.981504947 | 0.33480194 | 2.877378671 | 0.972862011 |
Her2 receptor status | 1.257944488 | 0.823912985 | 1.9206207 | 0.287844565 | 1.373910032 | 0.865382257 | 2.181265863 | 0.178008111 |
Tumor | 1.754711187 | 0.617255141 | 4.988231197 | 0.291488237 | 1.101502581 | 0.3254944 | 3.727584669 | 0.87648392 |
Lymph node status | 2.17751336 | 1.49200771 | 3.177975825 | 5.48E-05 | 1.651534043 | 1.069601814 | 2.550074858 | 0.023602411 |
Metastasis status | 2.520159824 | 0.343448624 | 18.49244717 | 0.363359385 | 1.858617241 | 0.226521566 | 15.25001838 | 0.563807742 |
Margin status | 0.7974526 | 0.396241415 | 1.604907073 | 0.525907749 | 0.634209273 | 0.307262431 | 1.309048428 | 0.218093787 |
Ethnicity | 0.634959689 | 0.086536008 | 4.659029397 | 0.655117076 | 1.014927373 | 0.132510023 | 7.773582306 | 0.988619118 |
Age | 0.97574987 | 0.948136617 | 1.004167323 | 0.093730595 | 0.979959839 | 0.95094581 | 1.009859108 | 0.186780098 |
Anatomic neoplasm subdivision | 1.039911088 | 0.843603069 | 1.281900351 | 0.713889548 | 0.97189382 | 0.782429155 | 1.207237219 | 0.796654191 |