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A schematic model presents the effect of tea polyphenols (TP) in attenuating STS-induced cytotoxicity in hippocampal neurons. STS treatment induced cytotoxicity and morphological collapse in neurons, whereas TP medication rescued the neurons from STS-induced toxicity by restoring the expression of BDNF and associated TrkB-Akt and Bcl-2/caspase-3 signaling pathway to inhibit apoptosis.
