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Time courses of serum CK, uGlc4, Gross Motor Quotient (GMQ) of PDMS-2, scores of GMFM-88 E domain, % of prediction of 6-min walk test, and management (ERT dosage and frequencies) for 21 IOPD patients. Patient No. 1 was not spotted for no complete detail of serum CK during these years. CK was plotted on the left Y-axis, while the other 4 values are plotted against the right Y-axis. 20 eow: 20 mg/kg every other week; 40 eow: 40 mg/kg eow; 20 qw: 20 mg/kg every week.
