Fig. 2.

Effect of BioE‐1115 on body weight, body composition, and organ weight in mice fed an HF‐HFrD. (A,B) Body weight of C57Bl/6 mice fed an HF‐HFrD and treated for 25 weeks with vehicle versus BioE‐1115 (A) over time and (B) at the day of sacrifice; the weights of mice fed an NCD were also measured at sacrifice. (C) Body fat, lean, and fluid mass measured by NMR in 23‐week‐dosed C57/Bl6 mice on an HF‐HFrD. (D) Liver and (E) muscle weights at sacrifice. All results represent mean ± SEM for 20‐25 male mice per group. P values are shown. *P < 0.05. Abbreviation: NS, not significant.