Fig. 7.

Effects of prolonged dietary phosphate load on renal expression of markers for renal inflammasome and dendritic cells. Wild‐type mice at 12 weeks of age were placed on a regular diet containing 0.35% Pi (NP) or 2.0% Pi (HP) for 4 weeks (N = 6 per group) or 8 weeks (N = 5 per group). Relative mRNA levels of Nod‐like receptor protein 3 (Nlrp3) (A), IL‐1β (B), Cd11c (C), and Ccr7 (D) are indicated. All data are presented as mean ± SD. *P < 0.05 vs mice fed 0.35% Pi for 4 weeks by Wilcoxon’s rank‐sum test.