TABLE 3.
Univariate cox regression of overall survival and clinicopathologic characteristics in TCGA HNSCCs patients.
Clinical characteristics (Univariate cox regression) | Hazard ratio | HR (95% CI) | p-value |
Age, years (≥60/<60) | 1.301 | 0.974–1.738 | 0.075 |
Gender (male/female) | 1.366 | 1.013–1.841 | 0.041 |
IGF2BP2 expression (low/high) | 1.014 | 1.004–1.025 | 0.007 |
Grade (G1/G2/G3/G4/Gx) | 1.061 | 0.898–1.254 | 0.487 |
Stage (I/II/III/IV) | 1.382 | 1.148–1.663 | 0.001 |
Local invasion (T1/2/3/4/Tx) | 1.153 | 1.028–1.294 | 0.015 |
Lymph nodes (positive/negative) | 1.164 | 1.071–1.264 | 0.000 |
Distant metastasis (M0/M1/Mx) | 0.974 | 0.751–1.320 | 0.974 |
HPV infection (positive/negative) | 1.808 | 0.519–6.293 | 0.352 |
Bold values indicate statistically significant, P < 0.05.