TABLE 1.

Natural products that modulates autophagy targeting cancer stem cells.

Natural products	Autophagy/mechanism	Cancer stem cells	References
Everolimus	PI3K/mTOR inhibitor	Breast cancer stem cells	Cavazzoni et al. (2012)
Salinomycin	Autophagy induction	Breast cancer stem cells	Zhao et al. (2019)
18α-Glycyrrhetinic acid and Gambogic acid	Induction/mTOR inhibition	Neuroblastoma brain cancer cells	Rahman et al. (2013, 2016)
Curcumin	Autophagy induction	Colon cancer stem cells	Huang et al. (2016b)
Resveratrol	Induction/mTOR inhibition	Colon cancer stem cells	Miki et al. (2012)
Rottlerin	PI3K/Akt/mTOR inhibition	Pancreatic CSCs	Singh et al. (2012)
Apigenin	PI3K/Akt/mTOR inhibition	CD34+ and CD38– leukemia cells	Cheong et al. (2010)
Alisertib	Akt/mTOR inhibition	Urinary bladder CSCs	Ding et al. (2015)
Trehalose	Autophagy induction	Prostate CSCs	Cristofani et al. (2018)
Gintonin	Induction/mTOR inhibitor	Neuroblastomas	Rahman et al. (2020a)