Table 3.

Overall survival analyses according to LMR change in 674 patients with ESCC.

Variables	Univariate			Multivariate
	HR	95% CI	P value	HR	95% CI	P value
NLRc	1.013	0.972-1.055	0.542
LMRc	0.670	0.515-0.870	0.003	0.687	0.526-0.898	0.006
PLRc	1.000	0.998-1.001	0.485
Sex	1.249	0.841-1.855	0.270
Age (years)	1.000	0.983-1.017	0.999
Pathology grade	1.566	1.228-1.998	<0.001	1.357	1.049-1.757	0.020
Depth of tumor	1.506	1.173-1.933	0.001	1.385	0.994-1.930	0.055
Lymph node metastasis	1.738	1.528-1.978	<0.001	1.746	1.416-2.154	<0.001
Pathological stage	1.897	1.538-2.342	<0.001	0.811	0.555-1.186	0.280
Vessel invasive	1.770	1.356-2.310	<0.001	1.172	0.875-1.570	0.287
Nerve infiltration	1.841	1.419-2.390	<0.001	1.535	1.164-2.025	0.002
Treatment regimen	1.012	0.9-1.137	0.847
Hospital time (days)	1.007	0.997-1.016	0.169