Table 2.
Comparison of general data in HF patients with different ejection fractions
| Projects | HFpEF group (≥50%, n = 60) |
HFmrEF group (41–49%, n = 28) |
HFrEF group (≤40%, n = 25) |
P value |
|---|---|---|---|---|
| Age (year) | 73.35 ± 11.31 | 68.82 ± 14.28 | 62.92 ± 16.79a | 0.021 |
| Male (case %) | 26 (43.3%) | 18 (64.3%) | 18 (72.0%) | 0.796 |
| BMI (kg/m2) | 23.95 ± 4.20 | 22.98 ± 3.03 | 23.03 ± 3.43 | 0.499 |
|
Systolic blood pressure (mm Hg) |
139.28 ± 27.64 | 139.44 ± 22.51 | 121.04 ± 17.25ab | 0.011 |
| Diastolic blood pressure (mmHg) | 76.07 ± 13.92 | 76.86 ± 14.76 | 78.20 ± 13.73 | 0.819 |
| Serum sodium (mmol/L) | 140.60 ± 3.95 | 140.36 ± 3.75 | 141.32 ± 3.02 | 0.607 |
| Fasting glucose (mmol/L) | 6.30 ± 1.11 | 6.54 ± 1.19 | 6.21 ± 0.97 | 0.504 |
| LVEF (%) | 57.19 ± 5.43 | 44.45 ± 2.99 | 33.23 ± 3.98 | <0.01 |
|
Triglyceride (mmol/L) |
1.39 ± 0.85 | 1.40 ± 0.74 | 1.38 ± 0.66 | 0.832 |
| Total cholesterol (mmol/L) | 4.04 ± 1.14 | 4.29 ± 1.24 | 4.25 ± 1.08 | 0.721 |
| LDL-C (mmol/L) | 2.54 ± 0.99 | 2.76 ± 1.08 | 2.85 ± 1.08 | 0.432 |
|
Serum Creatinine (μmol/L) |
132.08 ± 20.63 | 108.71 ± 49.31 | 104.12 ± 44.78 | 0.813 |
|
eGFR (ml/min/1.73m2) |
65.52 ± 3.94 | 55.99 ± 5.37 | 53.20 ± 8.48 | 0.237 |
|
ACEI/ARB [case (%)] |
22 (36.7%) | 13 (46.4%) | 7 (28%) | 0.383 |
|
β-blockers [case (%)] |
18 (30.0%) | 7 (25.0%) | 7 (28.0%) | 0.889 |
| MRA [case (%)] | 12(20.0%) | 8(28.6%) | 11(44.0%) | 0.079 |
Note: BMI Body Mass Index, LDL-C Low Density Lipoprotein Cholesterol, LVEF Left Ventricular Ejection Fraction, eGFR Estimated Glomerular Filtration Rate, 1 mmHg = 0.133 kPa, a: Compared with HFpEF group, b: Compared with HFmrEF: *P<0.05