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. 2019 Aug 8;105(5):1369–1378. doi: 10.3324/haematol.2019.223891

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Negative impact of BCL2 translocation on the outcome of patients with MYC-ICN. BCL2-ICN did not influence survival of patients with MYC-ICN, whereas BCL2-T negatively influenced the outcome of these patients compared to BCL2-WT and BCL2-ICN patients. Notably, among patients with MYC-ICN and BCL2-T, the group with >4 copies had a significantly worse prognosis than patients with ≤4 copies [median overall survival (OS) of 11 months compared to a 2.5-year OS of 75%, P=0.004] (data not shown).