Table 2. Treatment-Related Adverse Events.
| Adverse eventa | Grades, No. (%) (Nā=ā54) | |
|---|---|---|
| ā„3 | All | |
| Alkaline phosphatase increase | 2 (4) | 13 (24) |
| Lymphopenia | 1 (2) | 12 (22) |
| Aspartate aminotransferase increase | 0 | 11 (20) |
| Fatigue | 1 (2) | 11 (20) |
| Anemia | 1 (2) | 10 (19) |
| Alanine aminotransferase increase | 0 | 9 (17) |
| Vomiting | 0 | 9 (17) |
| Diarrhea | 0 | 6 (11) |
| Nausea | 0 | 6 (11) |
| Rash | 0 | 5 (9) |
| Hyponatremia | 3 (6) | 4 (7) |
| Infusion reaction | 0 | 4 (7) |
| Pruritus | 0 | 4 (7) |
| Elevated bilirubin | 1 (2) | 3 (6) |
| Hypothyroidism | 0 | 3 (6) |
| Thrombocytopenia | 0 | 3 (6) |
a
Reported in 5% or more of all patients, any grade.