Skip to main content
. Author manuscript; available in PMC: 2020 Aug 17.
Published in final edited form as: Org Lett. 2019 Jul 22;21(16):6447–6451. doi: 10.1021/acs.orglett.9b02342

Figure 2.

Figure 2.

Scope of the base-mediated MPV reduction of aromatic ketones. Conditions: substrate (1.0 equiv, 0.10 mmol), K3PO4 (4.0 equiv), reductant (2.5 equiv), and 1,4-dioxane (1.0 M) heated at 120 °C for 16 h in a sealed vial under an atmosphere of N2. Unless otherwise noted, yields reflect the average of two isolation experiments. a Yield determined by 1H NMR analysis using hexamethylbenzene as an external standard. b Reaction heated at 80 °C for 16 h.