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. 2020 Apr 29;2020(4):CD011365. doi: 10.1002/14651858.CD011365.pub2

Comparison 1. Tonsillectomy versus tonsillotomy.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Peri‐operative blood loss 8 610 Mean Difference (IV, Random, 95% CI) 14.06 [1.91, 26.21]
1.2 Peri‐operative blood loss (sensitivity analysis) 3 196 Mean Difference (IV, Random, 95% CI) 18.71 [‐30.45, 67.87]
1.3 Need for medical intervention within 7 days 16 1416 Risk Ratio (M‐H, Fixed, 95% CI) 1.75 [1.06, 2.91]
1.4 Need for medical intervention within 7 days (sensitivity analysis) 10 864 Risk Ratio (M‐H, Fixed, 95% CI) 1.57 [0.86, 2.87]
1.5 Behaviour (CBCL 6 months) 1 67 Mean Difference (IV, Fixed, 95% CI) ‐6.00 [‐12.98, 0.98]
1.6 Behaviour (CBCL 24 months) 1 67 Mean Difference (IV, Fixed, 95% CI) ‐0.30 [‐8.95, 8.35]
1.7 Measures of respiratory events during sleep (AHI 6 months) 1 25 Mean Difference (IV, Fixed, 95% CI) ‐0.58 [‐5.43, 4.27]
1.8 Recurrence of SDB symptoms (6 months) 3 186 Risk Ratio (M‐H, Fixed, 95% CI) 0.26 [0.03, 2.22]
1.9 Recurrence of SDB symptoms (6 months sensitivity analysis) 1 100 Risk Ratio (M‐H, Fixed, 95% CI) 0.20 [0.01, 4.06]
1.10 Recurrence of SDB symptoms (12 months) 4 206 Risk Ratio (M‐H, Fixed, 95% CI) 0.35 [0.04, 3.23]
1.11 Recurrence of SDB symptoms (12 months sensitivity analysis) 2 73 Risk Ratio (M‐H, Fixed, 95% CI) 0.35 [0.01, 8.11]
1.12 Recurrence of SDB symptoms (24 months) 1 65 Risk Ratio (M‐H, Fixed, 95% CI) 0.21 [0.01, 4.13]
1.13 Reoperation rates (12 months) 2 166 Risk Ratio (M‐H, Fixed, 95% CI) 0.32 [0.08, 1.28]
1.14 Reoperation rates (18 months) 1 41 Risk Ratio (M‐H, Fixed, 95% CI) 0.35 [0.02, 8.10]
1.15 Incidence of throat infection (6 months) 1 67 Risk Ratio (M‐H, Fixed, 95% CI) 0.55 [0.11, 2.79]
1.16 Incidence of throat infection (12 months) 2 174 Risk Ratio (M‐H, Fixed, 95% CI) 0.56 [0.19, 1.65]
1.17 Incidence of throat infection (24 months) 1 65 Risk Ratio (M‐H, Fixed, 95% CI) 0.13 [0.02, 0.97]
1.18 Duration of surgery 8 566 Mean Difference (IV, Fixed, 95% CI) ‐0.99 [‐1.97, ‐0.02]
1.19 Duration of surgery (sensitivity analysis) 4 251 Mean Difference (IV, Random, 95% CI) ‐2.59 [‐7.72, 2.53]
1.20 Severity of postoperative pain (24 hours) 4 368 Mean Difference (IV, Fixed, 95% CI) 1.09 [0.88, 1.29]
1.21 Severity of postoperative pain (24 hours sensitivity analysis) 2 109 Mean Difference (IV, Fixed, 95% CI) 0.46 [‐0.39, 1.31]
1.22 Severity of postoperative pain (2 to 3 days) 3 301 Mean Difference (IV, Random, 95% CI) 0.93 [‐0.14, 2.00]
1.23 Severity of postoperative pain (2 to 3 days sensitivity analysis) 1 40 Mean Difference (IV, Fixed, 95% CI) ‐0.60 [‐1.78, 0.58]
1.24 Severity of postoperative pain (4 to 7 days) 4 370 Mean Difference (IV, Random, 95% CI) 1.07 [‐0.40, 2.53]
1.25 Severity of postoperative pain (4 to 7 days sensitivity analysis) 2 109 Mean Difference (IV, Random, 95% CI) 0.87 [‐0.89, 2.64]
1.26 Days until analgesics no longer required 3 267 Mean Difference (IV, Random, 95% CI) 2.78 [1.92, 3.64]
1.27 Days until analgesics no longer required (sensitivity analysis) 1 74 Mean Difference (IV, Fixed, 95% CI) 1.30 [‐0.17, 2.77]
1.28 Return to normal diet 2 175 Mean Difference (IV, Random, 95% CI) 2.60 [1.16, 4.04]
1.29 Return to normal diet (sensitivity analysis) 1 74 Mean Difference (IV, Fixed, 95% CI) 1.70 [0.37, 3.03]
1.30 Return to normal activity 3 248 Mean Difference (IV, Random, 95% CI) 3.84 [0.23, 7.44]
1.31 Return to normal activity (sensitivity analysis) 2 156 Mean Difference (IV, Random, 95% CI) 4.24 [‐1.30, 9.78]