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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Clin Lung Cancer. 2018 Aug 22;19(6):e893–e900. doi: 10.1016/j.cllc.2018.08.008

Table 4.

Clinical and Laboratory Risk Factors for Development of Pneumonitis

Pneumonitis
Risk Factor Yes No P Valuea
RT history .133
 Previous TRT/chest wall RT 5 (18) 23 (82)
 No previous TRT 4 (7) 57 (93)
 Non-CNS radiation after ICI 3 (20) 12 (80) .165
Heavy smoking history (>50 PYH) 5 (22) 18 (78) 1.00
Inflammatory biomarkers
 ALI ≥ 18 2 (5) 40 (95) .170
 NLR ≥ 5 7 (14) 43 (86) .178
 PLR ≥ 237 4 (9) 42 (91) .739

Abbreviations: ALI = advanced lung cancer in= ratio; PLR platelet/flammation index; CNS central nervous system;ICI = immune checkpoint inhibitor; NLR neutrophil/lymphocyte lymphocyte ration; PYH pack-year =RT.= history; RT radiotherapy; thoracic= TRT using Fisher’s exact = test.

a

Association between categorical variables compared