Dietary modification influence on deaths as a result of breast cancer during cumulative follow-up. Kaplan-Meier cumulative hazard estimates for death as a result of breast cancer during the 19.6-year (median) cumulative follow-up among all 48,835 trial participants. Background shading shows the distribution for duration of the intervention phase (in quintiles); no shading indicates postintervention follow-up for all participants. Summary statistics are from a Cox proportional hazards regression model stratified by age-group, random assignment in the hormone therapy trials, hysterectomy status, ethnicity (white, black, other), and study period (time dependent). The P value corresponds to a 2-sided score (log-rank) test. HR, hazard ratio.