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. 2020 May 1;2020(5):CD011368. doi: 10.1002/14651858.CD011368.pub2

5.4. Analysis.

Comparison 5: Topical salicylic acid versus placebo, Outcome 4: Change in lesion counts ‐ inflamed (counts or %)

Change in lesion counts ‐ inflamed (counts or %)
Study Subgroup Salicylic acid Placebo P value
Eady 1996 Number reduction ‐ short, medium and long term (12 weeks after start of treatment) Unclear, not reported Unclear, not reported no difference; no difference; < 0.022
Shalita 1981 percent reduction ‐ short term 29.5% 20% not report and the author did not state whether this difference is significant
Shalita 1981 percent reduction ‐ medium term 44.6% 23% not report and the author did not state whether this difference is significant
Shalita 1981 percent reduction ‐ long term: 12 weeks after start of treatment 54% 29% not report and the author did not state whether this difference is significant