Change in lesion counts ‐ non‐inflamed (percentage reduction from baseline)
Study	Subgroup	Salicylic acid	No treatment	P value
Akarsu 2012	long term: 12 weeks after start of treatment	94.7%	81.1%	Quote:"The mean percent reductions in NIL, IL and TL counts were significantly higher for patients in group 1 as opposed to the patients in group 2 at week 12".
NilFroushzadeh 2009	long term: 12 weeks after start of treatment	open comedones:64.26% closed comedones:87.05%	open comedones:58.33% closed comedones:31.28%	open comedones: P > 0.05 closed comedones: P = 0.011