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(A) Experimental protocol for reversal of pulmonary hypertension showing timing of administration of MSC-EV, fibroblast extracellular vesicles (FL-EV), or PBS vehicle. (B and C) RVSP (B) and RV/LV + S (C) were measured 1 week after removal from 3 weeks of hypoxia. ***P < 0.001 and ****P < 0.0001.
