Table 4.
Adjusted hazard ratio* for incident cardiovascular disease
| Baseline REM-AHI | Follow-Up NREM-AHI and REM-AHI |
|||
|---|---|---|---|---|
| NREM-AHI | REM-AHI | Women | Men | |
| <5.0 | <5 | <5 | 1.00 (Reference) | 1.00 (Reference) |
| ≥5 | 1.15 (0.69–1.90) | 0.56 (0.32–0.98) | ||
| ≥5 | Any | 1.36 (0.73–2.50) | 0.98 (0.58–1.66) | |
| 5.0–14.9 | <5 | <5 | 0.69 (0.31–1.53) | 0.66 (0.27–1.59) |
| ≥5 | 1.60 (0.93–2.75) | 1.27 (0.73–2.20) | ||
| ≥5 | Any | 2.11 (1.14–3.90) | 1.17 (0.66–2.09) | |
| ≥15.0 | <5 | <5 | 1.00 (0.31–3.32) | 1.84 (0.42–8.03) |
| ≥5 | 1.02 (0.56–1.89) | 1.20 (0.68–2.12) | ||
| ≥5 | Any | 2.27 (1.17–4.43) | 0.53 (0.25–1.12) | |
Definition of abbreviations: NREM-AHI = apnea–hypopnea index during non–rapid eye movement sleep; REM-AHI = apnea–hypopnea index during rapid eye movement sleep.
*
Adjusted for age, body mass index, change in body mass index, race, smoking status, and prevalent hypertension, type 2 diabetes, or cardiovascular disease.