Table 1.
Demography and Characteristics at Baseline
| Parameter | Pitolisant (n = 201) | Placebo (n = 67) | All Patients (N = 268) |
|---|---|---|---|
| Age, yr, mean (SD) (range) | 51.9 (10.6) (25–75) | 52.1 (11.0) (30–76) | 52.0 (10.6) (25–76) |
| Sex, n (%) | |||
| M | 151 (75.1) | 51 (76.1) | 202 (75.4) |
| F | 50 (24.9) | 16 (23.9) | 66 (24.6) |
| Weight at inclusion, kg, mean (SD) | 97.7 (15.7) | 99.8 (16.1) | — |
| BMI, kg/m2, mean (SD) | 32.8 (4.6) | 33.0 (4.3) | — |
| Cardiovascular disease, n (%) | 110 (54.7) | 35 (52.2) | 145 (54.1) |
| AHI at date of diagnosis, events/h, mean (SD) | 50.2 (44.3) | 46.9 (22.8) | 49.3 (40.0) |
| Nocturnal SaO2 at date of diagnosis, %, mean (SD) | 89.8 (9.1) | 90.9 (3.8) | 90.1 (8.2) |
Definition of abbreviations: AHI = apnea–hypopnea index; BMI = body mass index.