Fig. 7.
SCD-associated UBIAD1 accumulates in ER membranes where it binds to HMG-CoA reductase and blocks its ERAD thereby disrupting cholesterol homeostasis.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.