TABLE 3.

Hepatic phospholipid fatty acid composition in NASH and antioxidant treatment

VitE	Chow		WD for 8 weeks		WD for 20 weeks
	(−)	(+)	(−)	(+)	(−)	(+)
16:0	18.54 ± 0.32	18.10 ± 0.26	19.58 ± 0.16a	20.43 ± 0.25b	20.71 ± 0.10a,c	20.46 ± 0.09
16:1	0.70 ± 0.14	0.76 ± 0.03	1.55 ± 0.04a	1.45 ± 0.05	1.92 ± 0.06a,c	1.93 ± 0.06
18:0	20.25 ± 0.39	19.40 ± 0.30	15.51 ± 0.23a	15.94 ± 0.21	15.29 ± 0.11a	14.97 ± 0.22
18:1ω9	8.50 ± 0.27	9.13 ± 0.23	13.09 ± 0.19a	13.18 ± 0.19	15.14 ± 0.16a,c	14.75 ± 0.16
18:1ω7	2.98 ± 0.19	2.97 ± 0.12	5.51 ± 0.22a	5.41 ± 0.15	6.49 ± 0.12a,c	6.28 ± 0.15
18:2	11.39 ± 0.51	11.06 ± 0.29	7.61 ± 0.29a	8.05 ± 0.17	7.03 ± 0.09a	6.80 ± 0.14
20:3ω6	3.45 ± 0.19	3.65 ± 0.11	3.81 ± 0.10	4.00 ± 0.11	3.48 ± 0.06	3.47 ± 0.04
20:4	19.06 ± 0.53	17.29 ± 0.18b	20.86 ± 0.37a	20.07 ± 0.14	20.77 ± 0.26a	21.02 ± 0.17
20:5	0.92 ± 0.22	1.26 ± 0.08	0.17 ± 0.07a	0 ± 0b	0 ± 0a	0 ± 0
22:4ω6	0 ± 0	0 ± 0	0.54 ± 0.07a	0.26 ± 0.08b	0.26 ± 0.11	0.72 ± 0.02b
22:5ω6	0 ± 0	0.20 ± 0.10	1.37 ± 0.09a	1.42 ± 0.11	0.52 ± 0.22c	1.43 ± 0.03b
22:5ω3	0.37 ± 0.12	0.75 ± 0.02b	0 ± 0a	0 ± 0	0 ± 0a	0.05 ± 0.05
22:6	13.84 ± 0.29	15.43 ± 0.28b	10.40 ± 0.21a	9.79 ± 0.10b	8.39 ± 0.23a,c	8.11 ± 0.09

Data are expressed as mean (percent of lipid composition) ± SEM, n = 8–11 mice.

^aP < 0.05 versus chow.

^bP < 0.05 versus no VitE treatment, same diet.

^cP < 0.05 versus WD for 8 weeks.