KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Troponin T-C	Santa Cruz	Cat#sc-8121; RRID:AB_2287642
GFP	Abcam	Cat#ab6673; RRID:AB_305643
Sarcomeric a-Actinin	Sigma	Cat#A7811; RRID:AB_476766
Bacterial and Virus Strains
Cre Recombinase Adenovirus (Ad-Cre-GFP)	Vector Biolabs	Cat#1700
eGFP Adenovirus (Ad-GFP)	Vector Biolabs	Cat#1060
Chemicals, Peptides, and Recombinant Proteins
Vybrant DyeCycle Violet	Invitrogen	Cat#V35003
Critical Commercial Assays
Superscript IV First-Strand Synthesis System	ThermoFisher	Cat#18090050
Power SYBR Green PCR Mastermix	Applied Biosystems	Cat#4367659
RNeasy micro Kit	QIAGEN	Cat#74004
RNA 6000 Pico Kit	Agilent	Cat#5067
Deposited Data
RNA-Sequencing	N/A	GEO: GSE140851
Experimental Models: Organisms/Strains
Mouse: Nkx2.5cre	Jackson Labs	Cat#024637
Mouse: ROSA26FLPe	Jackson Labs	Cat#009086
Mouse: Mlc2vcre	Jackson Labs	Cat#029465
Mouse: Ect2fl/fl: Ect2tm1a(EUCOMM)Wtsi	Institut Clinique de la Souris	MGI:4433090; RRID:IMSR_EM:09964
Mouse: R26REYFP	Jackson Labs	Cat#006148
Oligonucleotides
Genotyping Primers	See Table S1	N/A
qPCR Primers	See Table S2	N/A
Software and Algorithms
Prism 7.0	Graphpad	GraphPad Prism, RRID:SCR_002798
Fiji	ImageJ	Fiji, RRID:SCR_002285
R 3.2	R Project	R Project for Statistical Computing, RRID:SCR_001905
Picard Tools	Broad Institute	Picard, RRID:SCR_006525
GAGE	PMCID: PMC2696452, Bioconductor	GAGE, RRID:SCR_017067
NMF	R package	https://cran.r-project.org/web/packages/NMF/index.html
FactoMineR	R package	FactoMineR, RRID:SCR_014602
STAR 2.5	PMCID: PMC3530905	https://github.com/alexdobin/STAR
Limma	PMCID: PMC4402510, Bioconductor	https://bioconductor.org/packages/release/bioc/html/limma.html
MIQuant	PMCID: PMC3184116	https://paginas.fe.up.pt/~quelhas/MIQuant/MIQuant.zip
ToppGene Suite	PMCID: PMC2703978	ToppGene Suite, RRID:SCR_005726