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Cell cytotoxicity and antiviral activity of lycorine and brequinar.
| Cell line | CC50 (μM) | Lycorine EC50 (μM) | SI | CC50 (μM) | Brequinar EC50 (μM) | SI |
|---|---|---|---|---|---|---|
| Vero | 21 | 0.39 | 54 | >50 | 0.022 | >2272 |
| A549 | 4.29 | 0.22 | 19.5 | >50 | 0.046 | >1086 |
| Huh7 | 4.4 | 0.22 | 20 | >50 | 0.006 | >8333 |
SI: selectivity index.
