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. Author manuscript; available in PMC: 2020 Sep 2.
Published in final edited form as: Oncogene. 2020 Mar 2;39(17):3413–3426. doi: 10.1038/s41388-020-1234-3

Figure 1.

Figure 1.

Advantages and disadvantages of model system platforms in RCC.

Advantages and ideal applications, and disadvantages of traditional cell line, organoid, xenograft, and GEM models in RCC. As physiological relevance increases, ease of manipulation decreases.