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. Author manuscript; available in PMC: 2021 Feb 6.
Published in final edited form as: Cell. 2020 Jan 9;180(3):411–426.e16. doi: 10.1016/j.cell.2019.12.031

Figure 5. eIF4A Limits the Docking of P-bodies with SGs.

Figure 5.

(A) The number of PB/SG interfaces increase in the presence of arsenite in combination with Hipp compared to combinations of arsenite with PatA or arsenite alone.

(B–E) This effect holds true when interface quantities are normalized to the total amount or area of PBs (B and D) or SGs (C and E). PBs and SGs are visualized by EDC3 and G3BP1 IF, respectively. n ≥ 5 replicates. x represents the mean.

(F and G) Hipp addition produces a slight, but not significant, increase in PB number and area (F) but not in SG area (G).