Table 2. Mixed-model regression analysis examining changes in inflammatory markers and depressive symptoms over time.

Outcome/parameter	β	95%CI*	p-value	Delta deviance (%)
IL-6
Time†	0.43		NS	1.8
EPDS	0.04		NS
Sampling time	-0.07		NS
BMI	0.00		NS
IL-10
Time†	0.04		NS	0.2
EPDS	-0.04		NS
Sampling time	0.01		NS
BMI	0.01		NS
TNF-α
Time†	0.49		NS	0.9
EPDS	-0.06		NS
Sampling time	-0.05		NS
BMI	0.06		NS
CRP
Time† ‡	-1.58	-2.71 to -0.46	0.005	6.0
EPDS	0.01	-	NS
Pre-pregnancy BMI‡	0.30	0.15 to 0.46	< 0.001

95%CI = 95% confidence interval; BMI = body mass index; CRP = C-reactive protein; EPDS = Edinburgh Perinatal Depression Scale; IL-6 = interleukin-6; IL-10 = interleukin-10; NS = non-significant; TNF-α = tumor necrosis factor alpha.

^*95%CI values are reported only for significant effects.

^†Time refers to the difference between visits (third trimester vs. 12 weeks postpartum).

^‡Significant main effect for predictor/covariate (p < 0.05).