Table 1. Family-based association test of HTR1B gene polymorphisms.

Group/SNP/allele	Frequency	Informative families	z	p-value
ED (overall)
A-161T
A	0.692	72	3.232	0.001*
T	0.308	72	-3.232	0.001
G861C
G	0.608	65	-0.216	0.829
C	0.392	65	0.216	0.829
A1180G
A	0.745	64	1.897	0.057
G	0.255	64	-1.897	0.057
AN spectrum
A-161T
A	0.735	13	1.414	0.157
T	0.265	13	-1.414	0.157
G861C
G	0.547	14	-0.728	0.466
C	0.453	14	0.728	0.466
A1180G
A	0.744	17	0.600	0.548
G	0.256	17	-0.600	0.548
BN spectrum
A-161T
A	0.677	59	2.871	0.004*
T	0.323	59	-2.871	0.004
G861C
G	0.623	50	0.000	1.000
C	0.377	50	0.000	1.000
A1180G
A	0.748	47	1.723	0.084
G	0.252	47	-1.723	0.084

AN = anorexia nervosa; BN = bulimia nervosa; ED = eating disorders; HTR1B = serotonin receptor 1Dβ gene; SNP = single-nucleotide polymorphism.

^*Bonferroni’s correction: p ≤ 0.016.