Figure 4.

Two schematic drawings. (A) The essentially caudal‐rostral expansion (white arrows) of the Lewy body pathology in the brain after it attains a foothold in the dorsal motor nucleus of the vagus in the medulla oblongata (here, in black). The other consistently involved induction site in sporadic Parkinson's disease is the olfactory bulb (black). Reproduced with permission from Braak et al. [22]. (B) Median view of a mediosagittal section through the human brain: lines A and B indicate the respective planes of the frontal sections through the medulla oblongata depicted in Figure 1. Adapted and reproduced in part with permission from Del Tredici et al. [21].