Table 3.
Multivariable Logistic Regression Models for the Relationship Between Selected Characteristics and ≥5% Weight Gain, Stratified by Diagnostic Group
| EIBC |
DCIS |
Controls |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Weight gain ≥5% (N = 88) |
Weight gain <5% (N = 274) |
OR (95% CI)a |
Weight gain ≥5% (N = 31) |
Weight gain <5% (N = 147) |
OR (95% CI)a |
Weight gain ≥5% (N = 82) |
Weight gain <5% (N = 459) |
OR (95% CI)b |
|
| Median (IQR) | Median (IQR) | Median (IQR) | |||||||
| Age | 56 (49, 62) | 59 (51, 67) | 0.96 (0.93–0.99) | 53 (47, 59) | 56 (50, 65) | 0.94 (0.89–0.99) | 54.5 (48, 62) | 55 (49, 65) | 0.98 (0.96–1.01) |
| Vitality | 50 (35, 70) | 55 (35, 70) | 1.00 (0.99–1.01) | 50 (25, 70) | 55 (40, 75) | 0.99 (0.97–1.01) | 62.5 (50, 80) | 65 (50, 80) | 1.00 (0.99–1.02) |
| N (%)c | N (%)c | N (%)c | |||||||
|---|---|---|---|---|---|---|---|---|---|
| BMI | |||||||||
| Obese (≥30 kg/m2) |
24 (27.3) |
97 (35.4) |
0.81 (0.43–1.51) |
13 (41.9) |
50 (34.0) |
1.84 (0.60–5.64) |
29 (35.4) |
142 (30.9) |
1.64 (0.89–3.08) |
| Overweight (25 to <30 kg/m2) |
25 (28.4) |
88 (32.1) |
0.66 (0.35–1.24) |
10 (32.3) |
43 (29.3) |
1.70 (0.54–5.37) |
26 (31.7) |
138 (30.3) |
1.50 (0.81–2.76) |
| Normal weight (<25 kg/m2) |
39 (44.3) |
89 (32.5) |
Reference |
8 (25.8) |
54 (36.7) |
Reference |
27 (32.9) |
178 (38.8) |
Reference |
| Race | |||||||||
| African American |
9 (10.2) |
60 (21.9) |
0.23 (0.09–0.58) |
3 (9.7) |
29 (19.7) |
0.47 (0.12–1.87) |
18 (22.0) |
125 (27.2) |
0.49 (0.25–0.98) |
| White |
79 (89.8) |
214 (78.1) |
Reference |
28 (90.3) |
118 (80.3) |
Reference |
64 (78.0) |
334 (72.8) |
Reference |
| Marital status | |||||||||
| Married |
51 (58.0) |
163 (59.5) |
0.74 (0.39–1.42) |
21 (67.7) |
91 (61.9) |
1.67 (0.57–4.88) |
47 (57.3) |
289 (63.0) |
0.63 (0.35–1.13) |
| Not married |
37 (42.1) |
111 (40.5) |
Reference |
10 (32.3) |
56 (38.1) |
Reference |
35 (42.7) |
170 (37.0) |
Reference |
| Education | |||||||||
| ≤High school |
24 (27.3) |
92 (33.6) |
0.74 (0.40–1.36) |
9 (29.0) |
43 (29.3) |
1.20 (0.45–3.23) |
19 (23.2) |
116 (25.3) |
1.04 (0.56–1.96) |
| >High school |
64 (72.7) |
182 (66.4) |
Reference |
22 (71.0) |
104 (70.8) |
Reference |
63 (76.8) |
342 (74.7) |
Reference |
| Income | |||||||||
| <$50,000 |
45 (51.1) |
138 (50.4) |
1.73 (0.89–3.36) |
16 (51.6) |
68 (46.3) |
1.89 (0.66–5.43) |
32 (39.0) |
191 (41.6) |
0.72 (0.37–1.42) |
| Refused |
8 (9.0) |
22 (8.0) |
1.95 (0.73–5.20) |
2 (6.5) |
10 (6.8) |
2.03 (0.31–13.18) |
4 (4.9) |
32 (7.0) |
0.68 (0.22–2.10) |
| ≥$50,000 |
35 (39.8) |
114 (41.6) |
Reference |
13 (41.9) |
69 (47.9) |
Reference |
46 (56.1) |
236 (51.4) |
Reference |
| Smoking status | |||||||||
| Current smoker |
9 (10.2) |
43 (25.7) |
0.35 (0.14–0.86) |
3 (9.7) |
15 (10.2) |
0.75 (0.17–3.70) |
18 (22.0) |
46 (10.0) |
3.03 (1.49–6.17) |
| Former smoker |
29 (33.0) |
82 (29.9) |
1.03 (0.59–1.82) |
10 (32.3) |
53 (36.1) |
0.88 (0.34–2.27) |
28 (34.2) |
161 (35.1) |
1.33 (0.76–2.30) |
| Never smoker |
50 (56.8) |
149 (54.4) |
Reference |
18 (58.1) |
79 (53.7) |
Reference |
36 (43.9) |
252 (54.9) |
Reference |
| Radiation | |||||||||
| Yes |
65 (73.9) |
178 (65.0) |
1.71 (0.95–3.09) |
20 (64.5) |
81 (55.1) |
1.37 (0.50–3.75) |
— |
— |
— |
| No |
23 (26.1) |
96 (35.0) |
Reference |
11 (35.5) |
66 (44.9) |
Reference |
— |
— |
— |
| Chemotherapy and endocrine therapy | |||||||||
| Both |
20 (23.0) |
60 (21.9) |
0.44 (0.18–1.11) |
0 |
0 |
— |
— |
— |
— |
| Chemotherapy |
17 (19.5) |
37 (13.5) |
0.88 (0.34–2.29) |
0 |
0 |
— |
— |
— |
— |
| Endocrine therapy |
36 (41.4) |
146 (53.3) |
0.43 (0.19–0.95) |
13 (44.8) |
64 (44.1) |
0.99 (0.37–2.65) |
— |
— |
— |
| No | 14 (16.1) | 31 (11.3) | Reference | 16 (55.2) | 81 (55.9) | Reference | — | — | — |
a
Adjusted for age, vitality, BMI, race, marital status, education, income, smoking status, and treatment type. Bold type indicates statistical significance at p < 0.05.
b
Adjusted for age, vitality, BMI, race, marital status, education, income, and smoking status. Bold type indicates statistical significance at p < 0.05.
c
Percentages may not sum up to 100% due to rounding.