Table 1.
Baseline characteristics and epidemiology of patients with COVID-19 within and outside Wuhan.
| Guangzhou#1 (N = 20) | Wuhan#2 (N = 99) | P values | |
|---|---|---|---|
| Characteristics | |||
| Age, years, Mean (SD) | 43.2 (14.0) | 55.5 (13.1) | <0.001 |
| Range | 25–64 | 21–82 | |
| ≤39 | 9 (45.0%) | 10 (10.1%) | 0.002 |
| 40-49 | 4 (20.0%) | 22 (22.2%) | |
| 50-59 | 2 (10.0%) | 30 (30.3%) | |
| 60-69 | 5 (25.0%) | 22 (22.2%) | |
| ≥70 | 0 (0.0%) | 15 (15.2%) | |
| Sex | 0.198 | ||
| Female | 10 (50.0%) | 32 (32.3%) | |
| Male | 10 (50.0%) | 67 (67.7%) | |
| Chronic medical illness | 7 (35.0%) | 50 (50.5%) | 0.229 |
| Cardiovascular and cerebrovascular diseases | 5 (25.0%) | 40 (40.4%) | 0.209 |
| Digestive system disease | 3 (15.0%) | 11 (11.1%) | 0.703 |
| Endocrine system disease | 1 (5.0%) | 13 (13.1%) | 0.460 |
| Malignant tumor | 0 (0.0%) | 1 (1.0%) | 1.000 |
| Respiratory system disease | 1 (5.0%) | 1 (1.0%) | 0.309 |
| Admission to intensive care unit |
1 (5.0%) |
23 (23.2%) |
0.072 |
|
Signs and symptoms | |||
| Fever | 16 (80.0%) | 82 (82.8%) | 0.752 |
| Cough | 11 (55.0%) | 81 (81.8%) | 0.017 |
| Shortness of breath | 2 (10.0%) | 31 (31.3%) | 0.052 |
| Myalgia | 7 (35.0%) | 11 (11.1%) | 0.013 |
| Sore throat | 4 (20.0%) | 5 (5.1%) | 0.043 |
| Diarrhea | 5 (25.0%) | 2 (2.0%) | 0.001 |
| Nausea and vomiting | 3 (15.0%) | 1 (1.0%) | 0.015 |
| More than one sign or symptom | 18 (90.0%) | 89 (89.9%) | 1.000 |
| Fever, cough, and shortness of breath |
2 (10.0%) |
15 (15.2%) |
0.734 |
|
Comorbid conditions | |||
| Any | 3 (15.0%) | 33 (33.3%) | 0.118 |
| ARDS | 1 (5.0%) | 17 (17.2%) | 0.302 |
| Acute renal injury | 0 (0.0%) | 3 (3.0%) | 1.000 |
| Acute respiratory injury | 1 (5.0%) | 8 (8.1%) | 1.000 |
| Septic shock | 1 (5.0%) | 4 (4.0%) | 1.000 |
| Ventilator-associated pneumonia |
0 (0.0%) |
1 (1.0%) |
1.000 |
|
Epidemiological survey | |||
| Exposure to Huanan seafood market | 0 (0.0%) | 49 (49.5%) | <0.001 |
| Live history in epidemic areaa | 14 (70.0%) | 99 (100.0%) | <0.001 |
| Community cluster outbreak | 10 (50.0%) | 2 (2.0%)#3 | <0.001 |
| Close contacts with COVID-19 patient | 6 (30.0%) | NA | NA |
Data are n (%) unless specified otherwise. N is the total number of patients with available data. ARDS = acute respiratory distress syndrome. COVID-19 = coronavirus disease −19. P values for comparing two groups were derived using Fisher's exact test for categorized variables and t-test for continuous variables.
#1 Admitted to the Third Affiliated Hospital of Sun Yat-Sen University in Guangzhou from January 22 to February 12, 2020, the last follow-up was on February 18, 2020.
#2 Diagnosed in Wuhan Jinyintan Hospital from January 1 to January 20, 2020, the last follow-up was on January 25, 2020. #3 Only include the cases without long-term exposure to Huanan seafood market.
NA, not available.
Epidemic area refers to Wuhan and other epidemic areas in Hubei Province.