Table 2.
Comparison of Laboratory data and Outcome of Patients with COVID-19 Within and Outside Wuhan.
| Guangzhou#1 (N = 20) | Wuhan#2 (N = 99) | P values | |
|---|---|---|---|
|
Blood routine | |||
| Leucocytes ( × 109/L, normal range 3.5–9.5) | 5.2 (1.6) | 7.5 (3.6) | 0.006 |
| Lymphocytes ( × 109/L, normal range 1.1–3.2) | 1.4 (0.7) | 0.9 (0.5) | 0.003 |
| Platelets ( × 109/L, normal range 125.0–350.0) | 205.0 (62.6) | 213.5 (79.1) | 0.652 |
| Hemoglobin (g/L, normal range 130.0–175.0) |
139.3 (15.3) |
129.8 (14.8) |
0.010 |
|
Blood biochemistry | |||
| Increased alanine aminotransferase | 4 (20.0%) | 28 (28.3%) | 0.584 |
| Increased aspartate aminotransferase | 3 (15.0%) | 35 (35.4%) | 0.113 |
| Increased total bilirubin | 1 (5.0%) | 18 (18.2%) | 0.192 |
| Albumin (g/L) | 44.8 (5.6) | 31.6 (4.0) | <0.001 |
| Decreased | 1 (5.0%) | 97 (98.0%) | <0.001 |
| Increased serum creatinine | 1 (5.0%) | 3 (3.0%) | 0.526 |
| Increased creatine kinase | 5 (25.0%) | 13 (13.1%) | 0.183 |
| Increased myoglobin |
2/17 (11.8%) |
15 (15.2%) |
1.000 |
|
Infection-related biomarkers | |||
| Erythrocyte sedimentation rate (mm/h, normal range 0–15) | 19.3 (13.2) | 49.9 (23.4) | <0.001 |
| C-reaction protein (mg/L, normal range 0–6) | 25.0 (29.3) | 51.4 (41.8) | 0.002 |
| Procalcitonin (ng/mL, normal range 0–0.05) |
0.08 (0.09) |
0.5 (1.1) |
<0.001 |
|
Chest X-ray and CT finding | |||
| Unilateral pneumonia | 2 (10.0%) | 25 (25.3%) | 0.239 |
| Bilateral pneumonia | 18 (90.0%) | 74 (74.7%) | 0.239 |
| Multiple mottling and ground-glass opacity | 12 (60.0%) | 14 (14.1%) | <0.001 |
| Peripheral pneumonia | 17 (85.0%) | NA | NA |
| interstitial lesions | 16 (80.0%) | NA | NA |
| Ground-glass opacity | 16 (80.0%) | NA | NA |
| Multiple patches | 18 (90.0%) | NA | NA |
| Multiple Infiltration | 11 (55.0%) | NA | NA |
| Nodule | 4 (20.0%) | NA | NA |
| Lung consolidation | 4 (20.0%) | NA | NA |
| Pleural effusion | 2 (10.0%) | NA | NA |
Data are n (%) and mean (SD). N is the total number of patients with available data. COVID-19 = coronavirus disease −2019 P values for comparing two groups were derived using Fisher's exact test for categorized variables and t-test for continuous variables.
#1 Admitted to the Third Affiliated Hospital of Sun Yat-Sen University in Guangzhou from January 22 to February 12, 2020, the last follow-up was on February 18, 2020.
#2 Diagnosed in Wuhan Jinyintan Hospital from January 1 to January 20, 2020, the last follow-up was on January 25, 2020.
NA, not available.