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. 2020 Apr 24;83(1):e57–e60. doi: 10.1016/j.jaad.2020.04.094

Table I.

Summary of reported COVID-19 cases with cutaneous manifestations between January 1, 2020, and April 19, 2020

Authors No. Age, y and sex Cutaneous manifestations Extracutaneous manifestations Laboratory-confirmed COVID-19 case Associated with disease severity Skin biopsy Progression Article link
Reported cases with skin manifestations that indicate viral exanthems
 Guan et al 2 of 1099 NA NA NA Yes Yes No NA https://doi.org/10.1056/NEJMoa2002032
 Joob and Wiwanitkit 1 NA Skin rash with petechiae Fever, thrombocytopenia, respiratory symptoms Yes NA No NA https://doi.org/10.1016/j.jaad.2020.03.036
 Recalcati 18 of 88 NA Erythematous rash (n = 14), widespread urticaria (n = 3), chickenpox-like vesicles (n = 1) NA Yes No No NA https://doi.org/10.1111/jdv.16387
 Hunt and Koziatek 1 20, M Diffuse nonpruritic erythematous morbilliform rash on trunk and extremities Fever, multifocal pneumonia with decreased oxygen saturation Yes Yes No NA https://doi.org/10.5811/cpcem.2020.3.47349
 Mahé et al 1 64, F Erythematous rash on both antecubital fossa, trunk, and axillary folds resembling symmetric drug-related intertriginous and flexural exanthem Fever, cough, asthenia, bilateral pneumonia Yes No No Improved within 5 days https://doi.org/10.1111/jdv.16471
 Jimenez-Cauhe et al 1 84, F Mild pruriginous erythematous-purpuric, coalescing macules on the periaxillary area Bilateral pneumonia Yes NA No NA https://doi.org/10.1016/j.jaad.2020.04.016
 Marzano et al 22 8-90; 16M and 6F Diffuse/scattered papulovesicular lesions on trunk (n = 22) and extremities (n = 4), mild itch (n = 9), pain (n = 2), burning (n = 3) Fever, cough, headache, weakness, coryza, dyspnea, hyposmia, hypogeusia, pharyngodynia, diarrhea, myalgia Yes No Yes (n = 7) 4-15 days https://doi.org/10.1016/j.jaad.2020.04.044
 Lu et al 1 NA Urticaria Bilateral pneumonia with minimal symptom No No No NA https://doi.org/10.1002/jmv.25776
 Henry et al 1 27, F Generalized urticaria on face and extremities Odynophagia, arthralgia, chills, fever, chest pain Yes No No NA https://doi.org/10.1111/jdv.16472
 Fernandez-Nieto et al 1 32, F Urticaria NA Yes No Yes Improved within 5 days https://doi.org/10.1111/jdv.16470
 Hoehl et al 1 of 2 NA Faint rash Minimal pharyngitis Yes No No NA https://doi.org/10.1056/NEJMc2001899
Reported cases with vasculopathy-related skin manifestations
 Zhang et al 7 49-71; 4 M and 3 F Finger/toe cyanosis, skin bullae, and dry gangrene Fever, cough, dyspnea, diarrhea Yes Yes No NA https://doi.org/10.3760/cma.j.issn.0253-2727.2020.0006
 Mazzotta and Troccoli 1 13, M Erythematous-violaceous rounded lesions on toes with 1-cm diameter, tense blister, blackish crusts at 7 days later Low-grade fever, muscle pain, headache No No No Regressed in 2 weeks http://sectcv.es/wp-content/uploads/2020/04/acroischemia-ENG.pdf
 Manalo et al 2 67, M Transient nonpruritic blanching unilateral livedoid patch on right thigh Low-grade fever, nasal congestion, post-nasal drip, cough, hematuria Yes Yes No Resolved within 19 hours https://doi.org/10.1016/j.jaad.2020.04.018
47, F Unilateral transient asymptomatic rash on right leg resembling livedo reticularis Low-grade fever, mild headache, sinus pressure, anosmia Yes No No Resolved within 20 minutes
 Ma et al 1 of 3 69, M Dry gangrene on right index finger Fever, bilateral pneumonia, antiphospholipid syndrome with cerebral infarcts Yes Yes No NA https://doi.org/10.1016/j.clim.2020.108408
 Zhang et al 1 of 3 69, M Ischemia on both lower limbs and digits of the left hand Fever, bilateral pneumonia, diarrhea, headache, multiple cerebral infarcts, positive antiphospholipid antibodies Yes Yes No NA https://doi.org/10.1056/NEJMc2007575
 Alramthan and Aldaraji 2 27 and 35; 2 F Red-to-purple papules on the dorsal aspects of fingers (n = 2), diffused erythema in the subungual area of the right thumb (n = 1), clinical features resembling chilblains None Yes No No NA https://doi.org/10.1111/ced.14243
 Estebanez et al 1 28, F Confluent erythematous-yellowish papules on both heels, later developed into pruritic erythematous plaques resembling urticarial vasculitis Dry cough, nasal congestion, fatigue, myalgia, arthralgia, diarrhea, ageusia, anosmia Yes No No NA https://doi.org/10.1111/jdv.16474

F, Female; M, male; NA, not available.

References supporting this table are available from the corresponding author upon request.